This depot is another Spanish Mediterranean design by McCoy, with some stylistic variations from those of Brownsville (
BS18) and McAllen. The coming of a second rail line through Edinburg to the Mexican border indicated that the region could no longer sustain its exponential economic growth solely with the 1904 rail line to Harlingen. The depot was rehabilitated in 1996 as a visitors' center and office for the Edinburg Chamber of Commerce.

In the vicinity, the campus of the University of Texas–Pan American, at 1201 W. University Drive, was planned by Kenneth Bentsen and Associates in the late 1960s and 1970s as a contemporary exploration of the Border Brick style that set the tone for later additions by other architectural firms.