The 1791 fieldstone portion of Greene Academy was built as an Episcopal church on land owned by James Carmichael during a time when the threat of Native American attack was ever present. The brick extension of 1810 housed the only post-elementary-level school in Greene County until 1849, when the school moved to Waynesburg College (now University, GR3). Women were accepted to Greene Academy in 1837. The academy housed the local public school from 1865 to 1893. Subsequently, the building has housed the local post of the Grand Army of the Republic, three apartments, and, after restoration, a community center. Greene Academy is a plain, two-and-one-half-story rectangular building. The stone portion at the north end is two bays in length and three bays across the facade. First-floor openings have segmental stone arches, as does the entrance, with double doors facing Market Street. The brick addition is three bays on all elevations and has a more regular fenestration. The gable roof has been replaced with a standing-seam metal roof topped with a cupola. The building now houses the local center for the arts.