In the 1830s, Wellsboro citizens faced a choice of calling an Episcopal priest or a Presbyterian minister. Local sentiment favored the former, leaving New Englanders, who identified with Presbyterianism's Puritan roots, to wait until 1843 to organize Wellsboro's First Presbyterian Church. Their first church, an 1854 frame building, was demolished for the construction of the present church, the work of a prominent Williamsport partnership. The Gothic Revival church is built of random rock-faced Ohio sandstone. A large tracery window dominates the nave, which is flanked by towers of different heights, both capped by pyramidal spires. A rounded turret provides a transition from the nave to the taller tower. Three doors lead to the vestibule and into the sixty-foot-square auditorium where four oakencased steel trusses rise from corner corbels to support the roof. The church enjoys four styles of stained glass, three from Lamb Studios (1890s, 1920s, 1940) and one by Willet Studios of Philadelphia (1997). New pews were installed in the mid-1960s.